Polymorphisms associated with taxane sensory neuropathy 1 Replication of Genetic Polymorphisms Reported to be Associated with Taxane-Related Sensory Neuropathy in Early Breast Cancer Patients treated with Paclitaxel
نویسندگان
چکیده
1 Department of Oncology and Strangeways Research Laboratory, University of Cambridge, Cambridge, UK 2 Cambridge Breast Unit and NIHR Cambridge Biomedical Research Centre, University of Cambridge NHS Foundation Hospitals, Hills Road, Cambridge, UK 3 Cancer Research UK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, UK 4 Cambridge Experimental Cancer Medicine Centre, Cambridge, UK 5 Warwick Clinical Trials Unit, University of Warwick, UK 6 Cancer Research UK Clinical Trials Unit (CRCTU), University of Birmingham, UK
منابع مشابه
Replication of Genetic Polymorphisms Reported to Be Associated with Taxane-Related Sensory Neuropathy in Patients with Early Breast Cancer Treated with Paclitaxel--response.
PURPOSE Associations between taxane-related sensory neuropathy (TRSN) and single-nucleotide polymorphisms (SNP) have previously been reported, but few have been replicated in large, independent validation studies. This study evaluates the association between previously investigated SNPs and TRSN, using genotype data from a study of chemotherapy-related toxicity in patients with breast cancer. ...
متن کاملPredictive Biomarkers and Personalized Medicine Replication of Genetic Polymorphisms Reported to Be Associated with Taxane-Related Sensory Neuropathy in Patients with Early Breast Cancer Treated with Paclitaxel
Purpose: Associations between taxane-related sensory neuropathy (TRSN) and single-nucleotide polymorphisms (SNP) have previously been reported, but few have been replicated in large, independent validation studies. This study evaluates the association between previously investigated SNPs and TRSN, using genotype data from a study of chemotherapy-related toxicity in patients with breast cancer. ...
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